Clustering-Induced, Clathrin-Mediated Endocytosis (CIC-ME) for Cancer Therapy

Despite the many efforts to discover novel ways of treating cancer, it is still a major health problem. Cancer is characterized by the uncontrolled cell growth of cells that have acquired self-sufficiency in growth signalling and/or unlimited replication 2. Such cells are often insensitive to anti-proliferating signals and are able to evade apoptosis. For therapy, solid tumors are generally removed by surgery.