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Transcriptomic studies in human ageing and longevity
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The life expectancy of the general western population has increased dramatically in the last 200 years (1) and is generally expected to continue this rise. Many people reach a high age, but at the same time on average 25% of the lifespan is spent in disability...

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Using functional genetics to identify components of cancer relevant signaling pathways
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Signaling pathways have pivotal roles in the cell's physiology. They relay information from the cell's outside to the cell's interior and vice versa. This way cells can dynamically react to changing conditions in the extracellular milieu, communicate with other cells and make cell fate decisions like proliferation, cell growth, differentiation, apoptosis and migration...

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