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Applications of Evolutionary Computation to Cryptology
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The world has become a global village. This statement represents more than just a phrase. When Karinthy published his “Six degrees of separation” theory more than 80 years ago, it sounded almost unbelievable. Despite the fact that the human population grew several times larger in the meantime, that theory sounds more true today than ever before (although, strictly speaking it is not true if we consider isolated Amazonian tribes, for example)...

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Arrhythmogenic CardiomyopathyImpact of Genotype, Clinical Course, and Long-Term Outcome
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Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) is a hereditary cardiomyopathy characterized by an increased risk of sudden cardiac death (SCD) and ventricular arrhythmias with primarily right ventricular (RV) involvement. However, predominant left ventricular (LV) forms are increasingly recognized. Moreover, on the molecular level, both ventricles are affected in a similar manner...

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Assessing barriers to the involvement of emergency departments in organ donation
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Organ transplantation has become increasingly successful in terms of patient survival and is currently the best treatment option for patients with organ failure. With living donor opportunities only being available for certain organs, most efforts are aimed to increase donation rates from deceased donors...

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Asthma in children: origins and outcomes
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Childhood asthma is an inflammatory disease of the airways characterized by episodes of airflow obstruction, often in response to triggers like infections, allergens, exercise and emotions. The prevalence of childhood asthma and asthma-like symptoms has dramatically increased during the end of the last century...

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Atrial Fibrillation: To Map Or Not To Map
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The outline of this thesis is provided in chapter 1. In summary, the aims of this thesis were to examine 1) the clinical applicability of a novel, intra-operative high resolution, multi-site epicardial mapping approach of the entire atria as a routine procedure during cardiac surgery, 2) whether there are preferential sites of electropathology during sinus rhythm in patients with various underlying heart diseases, 3) the relevance of conduction abnormalities during sinus rhythm at Bachmann’s Bundle, 4) the role of endo-epicardial asynchrony in persistence of AF, 5) characteristics of post-operative atrial ectopy and AF, 6) the relation between electrical parameters assessed with high resolution mapping, atrial ectopy and post-operative AF...

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