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Contents




                 Chapter 1     General introduction                                      7

                 Part I Telehealth and digital technology
                 Chapter 2     The current use of telehealth in ALS care and the barriers    19
                               to and facilitators of implementation: A Systematic Review

                 Chapter 3     Telehealth as part of specialized ALS care: feasibility and    47
                               user-experiences with “ALS home-monitoring and coaching”

                 Chapter 4     Patient perspectives on digital healthcare technology in    67
                               care and clinical trials for motor neuron disease: An
                               international survey

                 Part II Remote monitoring of respiratory function

                 Chapter 5     Using patient-reported symptoms of dyspnea for           95
                               screening reduced respiratory function in patients with
                               motor neuron diseases

                 Chapter 6     Home-monitoring of vital capacity in patients with motor    117
                               neuron disease

                 Chapter 7     General discussion                                      135


                               Summary                                                 157
                               Samenvatting (Summary in Dutch)                         163
                               Dankwoord                                               173
                               About the author                                        181
                               List of publications                                    183
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