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Table of contents




                CHAPTER 1  Introduction and outline of the thesis                        9

                CHAPTER 2  The anti-PLA2R antibody in membranous nephropathy:  What we
                            know and what remains a decade after its discovery          19
                            Kidney International (2019) 96, 1292–1302

                BIOMARKERS                                                              41

                CHAPTER 3  Differences between albumin assays: a note of caution        43
                            Kidney International (2019) 95, 1514–1517

                CHAPTER 4  Anti-PLA2R1  antibodies  as  prognostic  biomarker  in  membranous
                            nephropathy                                                 57
                            Kidney International Reports (2021) 6, 1677–1686

                THERAPY                                                                 87

                CHAPTER 5  Synthetic ACTH in high risk patients with idiopathic membranous
                            nephropathy: A prospective, open label cohort study         89
                            Plos One 2015 Nov12;10(11)

                CHAPTER 6  Pharmacological treatment of primary membranous nephropathy in
                            2016                                                       107
                            Expert review of clinical pharmacology (2016)9(11), 1463-1478

                CHAPTER 7  Immunological remission in PLA2R-antibody associated membranous
                            nephropathy (MN): Cyclophosphamide versus Rituximab        137
                            Kidney International (2018) 93, 1016–1017

                CHAPTER 8  Antibody guided therapy in patients with PLA2R-associated
                            membranous nephropathy                                     143
                            Submitted

                CHAPTER 9  Summary and Discussion                                      171

                Appendix    Samenvatting                                               199
                            Research data management                                   201
                            PhD portfolio                                              203
                            List of publications                                       205
                            Curriculum Vitae                                           207
                            Acknowledgements – Dankwoord                               209
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