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CHAPTER 11 Barriers and facilitators for therapeutic drug monitoring of beta-
lactams and ciprofloxacin in the ICU: a nationwide cross-sectional
study 197
CHAPTER 12 The effect of therapeutic drug monitoring of beta-lactam and
fluoroquinolones on clinical outcome in critically ill patients: the
DOLPHIN trial protocol of a multi-centre randomised controlled trial 221
CHAPTER 13 Cephalosporin-related neurotoxicity in a critically ill child: a call for
ceftriaxone therapeutic drug monitoring 237
PART IV FUTURE DIRECTIONS OF THERAPEUTIC DRUG MONITORING 247
CHAPTER 14 Therapeutic drug monitoring of antibiotics in critically ill patients:
current practice and future perspectives with a focus on clinical
outcome 249
CHAPTER 15 Model-informed precision dosing of antibiotics in pediatric
patients: a narrative review 267
CHAPTER 16 A review of scavenged sampling for sustainable therapeutic drug
monitoring: do more with less 291
CHAPTER 17 General discussion and future directions 309
APPENDICES Summary 347
Nederlandse samenvatting (Dutch summary) 353
List of publications 358
Affiliations of co-authors 360
PhD portfolio 363
About the author 365
Dankwoord (Acknowledgements) 366